According to a study at the University of Cincinnati, in patients with severe obesity who underwent bariatric (obesity surgery), the risk of cancer is reduced by at least third. The results were published in the Annals of Surgery.
"We found that Bariatrics reduces the risk of cancer, especially in the case of cancers associated with obesity, including breast cancer in postmenopausal women, endometrial cancer, pancreatic and colon cancer," - explains Daniel Schauer, MD, a leading researcher .
The study analyzed medical data 22,198 patients who underwent bariatric surgery, and 66,427 patients without surgery between 2005 and 2012, with follow-up until 2014. Data derived from the integrated systems of health insurance and health services research centers in California, Oregon, Washington and Colorado. At the same time, women made up more than 80 percent of patients.
According to the results of published studies, patients undergoing bariatric surgery, the risk of contracting cancer is 33 percent lower than in the other cases. According to scientists, this is especially noticeable in the oncological diseases associated with obesity. The risk of breast cancer decreased by 42 percent in postmenopausal women, and the risk of endometrial cancer - by 50 percent in patients with severe obesity. The risk of developing colon cancer fell by 41 percent, and pancreatic cancer - by 54 percent.
"The risks of breast cancer in postmenopausal women and endometrial cancer are closely related to estrogen levels, - says Schauer. - Weight Height lowers estrogen levels. "
Bariatric surgery helps reduce the risk of diabetes and insulin, which is a risk factor for cancer of the pancreas.
"Given the fact that the risk of developing cancer - one of the factors when considering bariatric surgery, there are other factors that should be considered. Reduction of diabetes and hypertension and improvement in survival and quality of life is reason enough ", - says Schauer.
The study found no significant association between bariatric surgery and the risk of cancer among men. According to Schauer, this may be due to the fact that the vast majority of the studied patients - women, and most cancers affect only them.
To assess the incidence of cancer 10 years after bariatric surgery used Cox proportional hazards models. After observing the 3.5 years the researchers identified 2543 cases of cancer.