Women with a lower probability of head and neck cancer received intensive chemotherapy and radiation, and have an increased relative risk of death from this type of cancer compared to other causes, according to a study presented at the annual meeting of the American Society of Clinical Oncology , held from 1 to 5 June in Chicago.
Annie Park, a doctor from Kaiser Permanente in Santa Clara, California, and her colleagues identified 884 patients with head and neck cancer diagnosed between 2000 and 2015 from a cancer registry Kaiser Permanente in Northern California. The results of treatment were evaluated for 223 women and 661 men with stage II to IVB HNC.
The researchers found that 271 patients died of cancer, and 93 died from non-cancerous causes of supervision with an average of 2.9 years. Women much less frequently than men receiving intensive chemotherapy (35 vs. 46%) and radiation (60 vs. 70%). In a pooled analysis of competing events hazard ratio of death from head and neck cancer compared with other causes was increased for women (adjusted relative risk 1.92), which indicates that the patient may be subjected to more severe treatment.
"We have not sought gender differences, so the results were truly amazing," - said co-author in a statement. "In addition to treatment, there are several factors that may contribute to differences in the results between women and men with head and neck cancer, and it is clear that we need to conduct more research."