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Treatment of patients after a heart attack depends on Cancer

October 27, 2017 12:42

According to a study published in the edition of the European Heart Journal: Acute Cardiovascular Care, treatment of patients with a heart attack depends on their history of cancer. A study of 35,000 patients who had a heart attack, has shown that the presence of cancer drugs recommended people do not get enough, so that the risk of mortality increases.

"It is well known that patients with cancer may be at increased risk of cardiovascular disease as a result of the treatment, - says the study's senior author, Dr. Dragan Radovanovic, Head of AMIS Plus Data Center in Zurich, Switzerland. - On the other hand, little is known about the treatment of cancer patients with myocardial infarction. "

Scientists have studied whether people received with myocardial infarction and cancer the same treatment as patients without cancer . The study included 35 249 participants included in the register of acute myocardial infarction in Switzerland (AMIS Plus) in the period from 2002 to mid-2015. Of these, 1981 (5.6%) had cancer.

To evaluate the researchers formed two groups of 1981 patients in one group were patients with a history of cancer, and the other - who did not have cancer. In this case, researchers took into account age, gender, and cardiovascular risk factors.

In each group, patients researchers compared indicators that received drug therapy in acute myocardial infarction and percutaneous coronary intervention (PCI) in order to open blocked arteries. They also compared the performance of hospital complications and mortality between the two groups.

Researchers have found that cancer patients are less exposed and less likely to receive PCI P2Y12 blockers and statins. The hospital mortality was significantly higher than it was in patients with cancer. Patients with a history of cancer were more likely to complications in the hospital. It is estimated they have a 44% greater chance of cardiogenic shock, a 47% greater chance of bleeding and 67% more likely to develop heart failure than patients without cancer.

"Patients with a history of cancer is less likely to receive adequate therapy for the treatment of myocardial infarction, they have 24% less likely to undergo PCI, 18% less likely to get P2Y12 antagonists and 13% less likely to statins. These patients had more complications and a 45% greater risk of dying in the hospital - said Dr. Radovanovic. - More research is needed to find out why cancer patients receive suboptimal treatment of myocardial infarction and have lower rates of treatment. "

The possible causes may be the type and stage of cancer, or serious comorbidities. Some patients with cancer can be a very limited life expectancy and refuse treatment of a myocardial infarction.



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