According to a new study published in the journal Radiology, a new technique that uses mammography to determine the biological composition of the tumor tissue can help reduce unnecessary breast biopsy.
Mammography was effective in reducing mortality from breast cancer by detecting cancer in its earliest, most treatable stages. However, many women are recalled for additional diagnostic imaging and, in many cases, a biopsy, to detect abnormal results, which eventually turned out to be benign. According to research estimates that in the United States, the figure is over 10 percent.
Dr. Drucker and his colleagues recently studied a new technique called triple breast imaging. John Shepard, Ph.D., now the University of Hawaii in Honolulu, and his team developed a three-component imaging the breast, when he studied at the University of California at San Francisco. By measuring the water content of lipids and proteins in the mammary gland tissues, the biological technology may provide a characteristic of the tumor. For example, more water can indicate tumor tissue angiogenesis or the formation of new blood vessels, it is an early sign of cancer.
For the study, researchers obtained mammograms from two tumors from the 109 that were suspicious or predrospolozheny to malignant neoplasms - the types of lesions that typically must undergo biopsy. Subsequent biopsy showed 35 samples were invasive cancer, while the remaining 74 were benign.
Images ternary imaging breast were obtained from mammograms and analyzed with radiomechanical mammography, a method that uses artificial intelligence algorithms for analyzing images and models - some of which are difficult for the human perception.
Image Analysis The combination of breast imaging and radiomiki ternary improved positive predictive value or the ability to predict breast cancer. The combined method has improved the positive predictive value of 32 percent only for visual interpretation to nearly 50 percent from nearly 36 percent reduction in biopsies. ternary breast imaging method -radiomiki missed one of 35 types of cancer, at a sensitivity of 97 percent.
Dr. Drucker said that a combined approach can play an increasingly prominent role in the diagnosis of breast cancer. She noted that the three breast imaging can be easily added to mammography without requiring major modifications to existing equipment.
"The patient is already receiving a mammogram, plus we get all this additional information with only 10 per cent more radiation dose", - she said.
This approach is still experimental at this stage, and further work is needed to make it available to patients. The researchers plan to explore how a combined approach will help radiologists make a final decision. They also want to study the approach of using digital tomosynthesis breast, which is sometimes referred to as "three-dimensional" mammography, which reduces the problem of overlapping breast tissue, inherent in conventional mammography. Dr. Drucker said that the unique water-lipid protein characteristic of tumors may be even more clear when tomosynthesis.