A new study published in the «Journal of the National Cancer Institute» journal, showed that patients who were cured of uterine body cancer (endometrial), often suffer from cardiovascular problems after therapy.
Endometrial cancer - one of the most commonly diagnosed types of cancer (in fourth place) and one of the most common causes of death from cancer (in sixth place) among women in the US. In 2017 in the United States, there were about 757,200 cases of recurrence of endometrial cancer and 10,920 deaths of patients.
Previous studies examining the long-term health effects among patients who have recovered from the uterine body cancer, concerned the quality of life, mental health, obesity, and the side effects associated with sex life. But the high overall survival rate of patients, the use of more sophisticated methods of treatment, high mortality from cardiovascular diseases among survivors of endometrial cancer, the study highlights the need for other long-term health consequences.
In the new study, the researchers identified 3621 patients who had undergone endometrial cancer using Database Utah population. They studied the diagnostic data on women (18 years and older) with this type of cancer for the 1997-2012 year.
Survey results indicate that about 25.7% of the survivors have been diagnosed with cardiovascular disease after 5-10 years after the cancer is detected. Surviving 47% more likely to suffer from heart disease within five years after the discovery of the tumor, and 33% more likely to have been diagnosed with cardiovascular problems after 5-10 years after the initial diagnosis of cancer.
In the surviving patients after 1-5 years after the diagnosis of cancer, there was an increased risk of peripheral vascular and atherosclerosis, hypotension, phlebitis, thrombosis, embolism, and other circulatory diseases, veins, and lymph nodes, as well as pulmonary heart disease, atrial fibrillation.
Increased risk of certain cardiovascular diseases persisted even after five to ten years after the diagnosis of endometrial cancer. Compared with patients who underwent surgery to remove the tumor, patients undergo additional radiotherapy / chemotherapy are at increased risk of cardiovascular disease within one to five years after diagnosis. Old age and obesity are also risk factors for the development of hypertension and cardiovascular disease in survivors.
This study shows that increased monitoring of cardiovascular disease can help to improve the health of patients and to prevent cardiovascular problems 10 years after the diagnosis of endometrial cancer.