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Raman - a new method for detecting cancer cells

17 September 2018 17:41

A biopsy may show that the cancer cells are still in the body. EU-funded project, the IMAGINE, has developed a unique technology "optical biopsy tissue" to assess the size of the tumor.

Positive cancer after the operation field lead to an increased risk of progression and decreased survival. However, obtaining a clear field of malignant tumors can be very difficult during the operation.

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Early detection and appropriate surgical intervention are critical measures to reduce mortality from cancer. The inability to visualize the penetration of cancer cells into the wound is a serious problem in many areas of oncology. Currently, the boundary is studied in excised tumors. The first step is performed during the operation, and the second - after the procedure. This approach is laborious.

Radical new imaging technology in cancer surgery

IMAGINE (wide-range intraoperative probe marker analysis cancers) has developed a platform technology that can be used to assess invasive cancer. "By constructing the first large-scale Raman prototype for surgery and its assembly, we can now depict the phantoms (tissue structures that mimic the optical properties of tissue) and human cells / tissue," - he describes the head of the study, Dr. Mads Bergholt.

Raman spectroscopy - a unique optical method without a label based on the inelastic scattering of light which ensures tissue "optical biopsy" at the molecular level. This new type of imaging can improve the selectivity to accurately identify tumor cells. Thus, "it has the potential to improve the results of operations, as well as reduce medical costs and the burden on the individual patient," - explains Dr. Bergholt.

To complete the initial optical Raman prototype design optimization is required. IMAGINE provided clinical viability of successfully using a new approach to optical imaging, which provides a more efficient laser illuminated tissue.

MSCA has made significant progress since the imaging platform design Raman got a new idea of ​​the propagation of photons in tissue phantoms simulating the optical properties of tissues and cancer cells. Thus Fellowship paved the way for the further study of methods based on Raman method for detection and diagnosis of cancer.

Raman spectroscopy is a new biomolecular approach for targeting cancers.

Source: https://medicalxpress.com/news/2018-09-tumour-cancer-cell-margin.html

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