After ovarektomii risk of developing colorectal cancer increases by 30%. Such a conclusion was made by scientists after a 18-year-old observation of women who had undergone removal of the ovaries at the age of 15-49 years.
In addition, according to the results of multivariate analysis, women with bilateral ovariectomy had a risk of developing tumors in the two times higher than those with only one ovary removed. In the age group 40-49 years, the probability was much higher.
The study authors wanted to understand how hormonal factors associated with the development of colorectal cancer. "Obviously, it ovarektomiya alter levels of sex hormones. But how does this affect the occurrence of colorectal cancer, while it is not clear ", - scientists note.
Explaining the increased risk of developing colorectal cancer after oophorectomy in women, the authors suggested that for the younger is typical estrogen replacement after surgery.
Previous studies have also shown that in women aged 40 to 69 years after hysterectomy and bilateral oophorectomy, the risk of developing cancer of the rectum was higher by 42%.
"These data, combined with our study emphasize the need for more rigorous evidence when planning resection of normal ovaries," - says Bob Kronmayer.
Based on materials clinicaloncology.com